May/June 2005
Volume 25, Number 3

Theme: Pharmaceutical Manufacturing

Table of Contents

Articles

Implementing PAT Step by Step as a Process Optimization Tool
by Connie Langberg Heinzeand Jan Ruud Hansen
This article provides a straightforward step by step approach for gradually implementing PAT in existing manufacturing processes.
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In-Line Non-Contact Check-Weighing (NCCW) with Nuclear Magnetic Resonance (NMR) Presents New Opportunities and Challenges in Process Control by Jos Corver, Gisela Guthausen, and Andreas Kamlowski This article presents a novel check-weighing technique which measures the mass contents of each individual container using NMR. Download Article...

Reaping the Long-Term Benefits of Integrating Radio Frequency Identification (RFID) into Pharmaceutical Manufacturing by Vivek Bapat and Glenn Restivo This article presents a strategic approach to implementing RFID technology to ensure greater consumer safety. Download Article...

Equipment Cleaning in Clinical Trial Material Manufacturing and Packaging by Matthew Gerber, Deborah Perona, and Lisa Ray This article discusses cleaning validation vs. cleaning verification in addition to listing the minimum requirements needed prior to performing equipment cleaning processes in Clinical Trial (CT) Manufacturing and Packaging. Download Article...

Inert Milling Systems by Ruby Jacobson, P.Eng. This article discusses the reasons for inerting a mill, what methods to employ to determine if a product is explosive, and the various factors used to define explosibility. It compares inerting to other protection strategies and concludes with a review of the different inerting methods. Download Article...

Features and Possibilities of a Modern Multiple-Effect Water Still by Mika Pärkkä, Juha Mattila, and Teppo Nurminen This article presents the features and possibilities of a modern Multiple-Effect Water Still (MWS). Download Article...

Plant Reliability of an Off-Gas/Liquid Waste Incinerator by M. Giovinazzi, G. Iaquaniello, and B. Manduca This article discusses a survey performed at an Italian pharmaceutical facility, which considers the thermal treatment of off-gas and liquid waste. Download Article...

Country Profile: Puerto Rico by ISPE Puerto Rico Chapter This section takes a look at the pharmaceutical industry in Puerto Rico. Download Article...

2005 Facility of the Year Winner: NovoSeven® Manufacturing Facility by ISPE Novo Nordisk NovoSeven® Manufacturing Facility Employs Groundbreaking Modular Design Download Article...