September/October 1998
Volume 18, Number 5

Theme: Alternative Manufacturing Systems/Outsourcing

Table of Contents

Articles

Interviews Sidney Taurel, President and Chief Executive Officer, Eli Lilly and Company by Sidney Taurel Pharmaceutical Engineering Interviews Sidney Taurel, President and Chief Executive Officer, Eli Lilly and Company Download Article...

Just-in-Time Packaging and Distribution: A New Prescription for the Pharmaceutical Industry by Nicholas Sleep This article describes a new concept in which pharmaceuticals are packaged and supplied more directly to patients on a “made to order not to stock” basis. Download Article...

Succeeding with Manufacturing Execution Solutions by Francois Peignes & Jean Trouchaud This article summarizes information presented at a seminar conducted in late 1997 by Euriware, Laboratoires Fournier, and Lilly France, under the sponsorship of the ISPE France Affiliate. Download Article...

Barrier Isolation History and Trends by Jack Lysfjord & Michael Porter This article is a summary of survey results taken in the spring of 2000 on the use of barrier isolators in fill/finish applications in the parenteral industry. Download Article...

Design Requirements in a Multi-Product Manufacturing Facility by Dr. Frank Hannon & Donald H. Westermann, PE The factors that directed the building, equipment and control design for a start-up custom manufacturer of pharmaceutical intermediates and API’s are reported. Download Article...

Outsourcing Validation Results in Significant Cost Savings by Peter B. Gardner, PE This article describes the methods available to achieve a fully integrated construction and validation effort that will save both time and money in the completion of projects. Download Article...

Potent Compound Manufacturing in the Pharmaceutical Pilot Plant by Sidney A. Brookes, Jr, Jihchin Chung, Mary F. Cooke & Michael D. Hrytsak This article describes the case history of the manufacturing of a highly potent active pharmaceutical ingredient using containment technology, including equipment design, installation, qualification, special operating procedures and actual operating experience. Download Article...