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ISPE Glossary of Pharmaceutical and Biotechnology Terminology
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Base
Substance whose chemical reaction characteristic is to establish new bonds by the donation of electron pairs.
Publication Source: ISO/TC209 Working Groups at 2001-03-31 – Committee Draft ISO/CD 14644-6 “Cleanrooms and associated controlled environments” – Part 6: Terms and Definitions
Base
An electropositive element or radical that unites with an acid to form a salt. Or, a substance that when dissolved in water, dissociates to produce one or more hydroxyl ions (OH-). Strong bases or alkalis are irritating and may damage tissue.
Base
A key component of DNA and RNA molecules. Four different bases are found in DNA: adenine (A), cytosine (C), guanine (G), and thymine (T). In RNA, uracil (U) substitutes for thymine. Also known as nitrogenous bases. A base, a phosphate molecule and a sugar joined together constitute a nucleotide.
See also: Anticodon
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