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The majority of the primary biological reference preparations referred to in the European Pharmacopeia are the appropriate International Standards and Reference Preparations established by the World Health Organization (WHO). Because these reference materials are usually available only in limited quantities, the Commission has established Biological Reference Preparations (indicated by the abbreviation BRP) where appropriate. Where applicable, the potency of the Biological Reference Preparation is expressed in International Units. For some Biological Reference Preparations, where an international standard or reference preparation does not exist, the potency is expressed in European Pharmacopeia Units.
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