ISPE Glossary of Pharmaceutical and Biotechnology Terminology

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Botulinum

An anaerobic, rod-shaped bacterium (Clostridium botulinum) that secretes botulin and inhabits soils. Clostridium botulinum produces 7 distinct toxins, types A through G. Botulinum toxin type A is the most studied of the 7 serotypes produced by the anaerobic bacterium Clostridium botulinum. Minute quantities of botulinum toxin type A offer significant potential in treating a wide variety of disorders associated with muscle overactivity. Botulinum toxin type A, currently commercialized under the trade name BOTOX®.

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