ISPE Glossary of Pharmaceutical and Biotechnology Terminology

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Buffer

A device or storage area (memory) used to store data temporarily to compensate for differences in rates of data flow, time of occurrence of events, or amounts of data that can be handled by the devices or processes involved in the transfer or use of the data.

Publication Source: FDA Glossary of Computerized System and Software Development Technology

Buffer

A substance capable of neutralizing both acids and bases in solution, thereby maintaining the original acidity or causticity of the solution.

Buffer

A solution containing a weak acid and a conjugate base of this acid; it resists change in its pH level when an acid or a base is added to it, because the acid neutralizes an added base and vice versa.

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