ISPE Glossary of Pharmaceutical and Biotechnology Terminology

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Escherichia Coli (E. Coli)

A fast growing, Gram-negative bacteria commonly found in the body with a comparatively simple structure. The genetic make up of E. coli is the best known of any organism, having been widely studied during the development of genetic engineering. It has been used extensively as the host cell for novel proteins made by rDNA technology.

Escherichia Coli (E. Coli)

A relatively harmless human intestinal bacterium. Laboratory strains of these bacteria have been kept for many years and are commonly used in the production of recombinant proteins.

Publication Source: ISPE Baseline® Guide, Vol. 6: Biopharmaceutical Manufacturing Facilities

Publication Date: 2004

See also: E. Coli (Escherichia Coli)

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