ISPE Glossary of Pharmaceutical and Biotechnology Terminology

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Factor IX (Hemophilia Factor)

In the clotting of blood, also known as Christmas factor (Biggs and Macfarlane). Deficiency of factor IX causes hemophilia B or Christmas disease that resembles hemophilia A and is an inherited defect that leads to a severe hemorrhagic disorder. Factor IX is required for the formation of intrinsic blood thromboplastin and affects the amount formed (rather than the rate).

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