ISPE Glossary of Pharmaceutical and Biotechnology Terminology

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An apparatus that maintain optimal conditions for the growth of microorganisms, used in large-scale fermentation and in the commercial production of antibiotics and hormones. Bioreactor used to grow bacteria or yeasts in liquid culture.

See also: Bioreactor


A tank or vessel used for carrying out fermentation. There are various choices of fermenters, depending on whether cells are suspended in the medium or attached to some type of support:

1. In suspension reactors

2. Attached growth reactors

3. Stirred-tank reactors

4. Airlift fermenters

5. Packed bed reactors

6. Two-chamber reactors

7. Hollow-fiber reactors

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