ISPE Glossary of Pharmaceutical and Biotechnology Terminology

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Intron; Intervening Sequence

A segment of DNA sequence of a eukaryotic gene, not represented in the mature (final) mRNA transcript, because it is spliced out of the primary transcript before it can be translated; a process known as intron splicing. Some genes of higher eukaryotes contain a large number of introns, which make up the bulk of the DNA sequence of the gene. Introns are also found in genes whose RNA transcripts are not translated, namely eukaryotic rRNA and tRNA genes. In these cases the intron sequence does not appear in the functional RNA molecule.

Publication Source: Food and Agricultural Organization of the United Nations (FAO)
Publication Date: 1999

See also: Exon

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