ISPE Glossary of Pharmaceutical and Biotechnology Terminology

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Isoelectric Point (pl)

The pH level above which the substance would act as a base and below which it would act as an acid. A solution of proteins or amino acids has its minimum conductivity and viscosity at the isoelectric point. The pI is a pH level established as a value for a given substance; for example, the pI of gelatin is pH 4.7.

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