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Also known as freeze drying, it is a means of stabilizing wet substances by freezing them, then evaporating the resulting ice, to leave a substantially dry, porous residue which has the same size and shape of the original frozen mass.
The creation of a solid from a liquid by means of freezing, sublimation, and desorption.
Publication Source: ISPE Baseline® Guide, Vol. 3: Sterile Manufacturing Facilities (First Edition)
Publication Date: 2011
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