ISPE Glossary of Pharmaceutical and Biotechnology Terminology

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Monoclonal Antibody (mAb or moAb)

Antibodies derived from a single source or clone of cells that recognize only one type of antigen. They are produced from hybridomas formed by the hybridization of two cells: a single antibody-producing cell and a cell that can be grown indefinitely in culture. Monoclonal antibodies have found markets in diagnostic kits and show potential for use in drugs and industrial purification processes.

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