ISPE Glossary of Pharmaceutical and Biotechnology Terminology

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Osmolality

The concentration of osmotically active particles in a solution (expressed in osmols of solute per liter of solution). Osmosis is flow through a semipermeable membrane. Osmotic pressure is the pressure that must be applied to a solution to prevent osmosis. Osmotic shock is rapid change in osmotic pressure of a cell or virus, usually causing it to discharge its contents.

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