ISPE Glossary of Pharmaceutical and Biotechnology Terminology

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Oxidizer

A chemical, which readily oxidizes more reduced substances. Examples of strong oxidizers are ozone, hydrogen peroxide, chloride, persulfates, and oxygen itself.

Publication Source: ISPE Baseline® Guide, Vol. 4: Water and Steam Systems (Second Edition)

Publication Date: 2011

Oxidizer

Any material other than a blasting agent or explosive that readily yields oxygen or other oxidizing gas, or that readily reacts to promote or initiate combustion of combustible materials.

Oxidizers are subdivided as follows:

1. Class 4 – An oxidizer that can undergo an explosive reaction due to contamination or exposure to thermal or physical shock. In addition, the oxidizer will enhance the burning rate and may cause spontaneous ignition of combustible materials.

2. Class 3 – An oxidizer that will cause a severe increase in the burning rate of combustible materials with which it comes in contact or that will undergo vigorous, self-sustained decomposition due to contamination or exposure to heat.

3. Class 2 – An oxidizer that will cause a moderate increase in the burning rate or that may cause spontaneous ignition of combustible materials with which it comes in contact.

4. Class 1 – An oxidizer whose primary hazard is that it slightly increases the burning rate but does not cause spontaneous ignition when it comes in contact with combustible materials.

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