ISPE Glossary of Pharmaceutical and Biotechnology Terminology

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Process Flow Diagram (PFD)

A schematic of the system which utilizes graphic symbols and text to illustrate the steps of an operation in proper sequence. A PFD should present a detailed, accurate, and ordered flow of raw material or ingredient through each manufacturing phase.

Publication Source: ISPE Baseline® Guide, Vol. 4: Water and Steam Systems (Second Edition)

Publication Date: 2011

Process Flow Diagram (PFD)

A detailed and accurate diagrammatic representation (drawing) of the sequential steps required for a specific process and/or utility system through each manufacturing phase.

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