ISPE Glossary of Pharmaceutical and Biotechnology Terminology

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Biological molecules having a number of functions within, and outside the cell. They consist of amino acids arranged like a string of pearls. Genes are “blueprints” for proteins.

Publication Source: ISPE Baseline® Guide, Vol. 6: Biopharmaceutical Manufacturing Facilities

Publication Date: 2004


One of a group of substances constituting the greater part of the nitrogen-containing components of animal and vegetable tissues. They are of very complex constitution, all containing carbon, hydrogen, nitrogen, and oxygen and some containing in addition iron, phosphorous, or sulfur; chemically they are regarded as peptides (polypeptides) or combinations of amino acids and their derivatives. They are colorless, odorless, generally tasteless, and of varying degrees of solubility; they are putrefiable and readily undergo chemical change, hydrolysis, under the influence of ferments and on boiling with dilute acids or alkalis. The word was coined by J?J. Berzelius (1838) to emphasize the importance of this group of molecules.

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See also: Amino Acids

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