ISPE Glossary of Pharmaceutical and Biotechnology Terminology

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Proteinaceous Infectious Particle; Prion

An abnormal form of a normal cell protein, with no detectable nucleic acid, found in the brain of mammals and believed to be the agent responsible for the class of diseases called spongiform encephalopathies, including scrapie in sheep and bovine spongiform encephalopathy (BSE; mad cow disease) in cattle.

Publication Source: Food and Agricultural Organization of the United Nations (FAO)
Publication Date: 1999

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