ISPE Glossary of Pharmaceutical and Biotechnology Terminology

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SDS-PAGE (Sodium Dodecyl Sulfate Polyacrylamide Gel Electrophoresis)

An analytical separation technique that uses a charged gel environment through which molecules of varying sizes and electric charges migrate from one pole to the other. Unlike gel-filtration chromatography, larger molecules move more slowly than smaller molecules because migration rate is not dependent on diffusion into and out of particles.

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