ISPE Glossary of Pharmaceutical and Biotechnology Terminology

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The precipitate that forms on surfaces in contact with water as the result of a physical of chemical change.

Publication Source: ISPE Baseline® Guide, Vol. 4: Water and Steam Systems (Second Edition)

Publication Date: 2011


The mineral deposit that can coat the insides of boilers or the surfaces of RO membranes. It consists mainly of calcium carbonate that precipitates out of solution under certain conditions of pH, alkalinity, and hardness.

See also: Saturation Index

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