ISPE Glossary of Pharmaceutical and Biotechnology Terminology

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Sequence Tagged Site (STS)

Short (200 to 500 base pairs) DNA sequence that has a single occurrence in the human genome and whose location and base sequence are known. Detectable by polymerase chain reaction, STSs are useful in chromosome placement, mapping and sequencing data reported from many different laboratories, and serve as landmarks on the developing physical map of the human genome. Expressed sequence tags (ESTs) are STSs derived from cDNAs.

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