ISPE Glossary of Pharmaceutical and Biotechnology Terminology

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Sticky Ends; Cohesive Ends

The single-stranded nucleotide sequence left on a restriction fragment by type II restriction enzymes that cut each strand at a separate location. These unpaired regions are available for hybridization with complementary ends on other fragments during the creation of recombinant DNA. Also known as Protruding End; Overhang; Cohesive End.

Publication Source: Food and Agricultural Organization of the United Nations (FAO)
Publication Date: 1999

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