ISPE Glossary of Pharmaceutical and Biotechnology Terminology

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Stress-Corrosion Cracking (SCC)

Failure by cracking under the combined action of corrosion and stress, either external (applied) or internal (residual). Cracking may be either intergranular or transgranular, depending on the metal and the corrosive medium.

Stress-Corrosion Cracking (SCC)

A type of corrosion that occurs due to sudden failure of normally ductile metals subjected to a constant tensile stress in a corrosive environment, particularly at elevated temperatures. This type of corrosion progresses rapidly. Certain austenitic stainless steels alloys crack in the presence of chlorides, which limit their usefulness for being in contact with solutions (including water) with higher, that a few ppm content of chlorides at temperature above 50°C. This form of corrosion is only applicable to the austenitic group of steels and is related to the nickel content; Ferritic grades do not generally suffer from this problem at all.

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