ISPE Glossary of Pharmaceutical and Biotechnology Terminology

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Total Organic Carbon (TOC)

A measure of the level of organic impurities in water by their carbon content that determines the operating life of activated carbon beds. This is one of the parameters used to determine the purity of Semiconductor Grade water. Feed water will have TOC measured in ppm (parts per million), and ultrapure water (UPW) will have TOC measured in ppb (parts per billion).

Total Organic Carbon (TOC)

Measure of organics in water by their Carbon content. This is one of the parameters used to determine the purity of Semiconductor Grade water. Feed water will have TOC measured in parts per million. UPW will have TOC measured in parts per billion (ppb).

Publication Source: ISPE Baseline® Guide, Vol. 4: Water and Steam Systems (Second Edition)

Publication Date: 2011

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