ISPE Glossary of Pharmaceutical and Biotechnology Terminology

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1. The uptake and establishment of DNA in a bacterium or yeast cell, in which the introduced DNA often changes the phenotype of the recipient organism.

2. Conversion by various means of animal cells in tissue culture from controlled to uncontrolled cell growth. Typically through infection by a tumour virus or transfection with an oncogene.

Publication Source: Food and Agricultural Organization of the United Nations (FAO)
Publication Date: 1999

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