ISPE Glossary of Pharmaceutical and Biotechnology Terminology

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Trihalomethanes (THMs)

Compounds present in the feed water that are formed by the reaction of chlorine and the organic material in the water. The most common THM found in water is chloroform, which is quite difficult to remove. Activated carbon and degasification can reduce THMs.

Publication Source: ISPE Baseline® Guide, Vol. 4: Water and Steam Systems (Second Edition)

Publication Date: 2011

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