Matthew VonEsch is the Senior Director of Manufacturing and Facilities for Sigma-Tau PharmaSource, a contract biopharmaceutical manufacturer, located in Indianapolis, Indiana. Beginning with Wyeth Biopharma, followed by Human Genome Sciences, MedImmune, and United Therapeutics, he has held positions of increasing responsibility in drug product manufacturing, including aseptic vial filling, automated inspection, and labeling and packaging operations. In 2013, Matthew joined Sigma-Tau PharmaSource as the Director of Manufacturing leading the restart of commercial operations following a redesign of the Parenteral Manufacturing Filling suites, which included the implementation of a RABS around their existing filling line. Following his operations leadership role for the manufacturing of the Drug Substance and Drug Product departments, in 2014, Matthew assumed responsibility for Product Engineering, Maintenance, Validation, and Technical Services in addition to his role with site Production. Matthew holds a BS in Biochemistry from the Merrimack College. He currently serves as Chair of the ISPE Sterile Products Processing COP Steering Committee.