Knowledge Brief: Containment Hierarchy of Controls

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by Beth Brock
Level: Fundamental

This Knowledge Brief will explain the basics of the Containment Hierarchy of Controls, as also described in ISPE's Baseline® Guide: Volume 1 – Active Pharmaceutical Ingredients. Information beyond the hierarchy described in the Baseline Guide has been added to illustrate alternative considerations typically contained in other versions of hierarchies, such as those used in Industrial Hygiene or Risk-Based Manufacture of Pharmaceutical Products (Risk-MaPP).

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Last Update: 14 September 2011

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