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ISPE Glossary of Pharmaceutical and Biotechnology Terminology
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Gamma Irradiation
A physical means of sterilization or decontamination also known as “Cold Process” (temperature of the processed product does not significantly increase) that uses electromagnetic radiation of very short wave lengths. Gamma Irradiation kills bacteria by breaking down bacterial DNA and inhibiting bacterial division.
The most common source of gamma rays for irradiation processing comes from the radioactive isotope Cobalt 60 which is manufactured specifically for the Gamma Irradiation process.
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