ISPE Glossary of Pharmaceutical and Biotechnology Terminology

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BAC (Bacterial Artificial Chromosome)

Large segments of DNA, 100,000 to 200,000 bases, from another species cloned into bacteria. Once the foreign DNA has been cloned into the host bacteria, many copies of it can be made.

BAC (Bacterial Artificial Chromosome)

A vector used to clone DNA fragments (100-kb to 300-kb insert size; average, 150-kb) in E. Coli cells. Based on naturally occurring F-factor plasmid found in the bacterium E. coli.

See also: Cloning Vector

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